Category Archives: Dementia

Pharmacological Treatment of Dementia

General guidelines for psychotropic medication use in frail elderly patients are applicable. Systematic evidence to support the effectiveness of particular psychotropic drugs in dementia patients is limited. Therefore, choice of drug class may be based on clinical evidence, and choice of agent is often based on the side-effect profile and on the characteristics of a… Read More »

Mixed Dementia and Dementia in Disseminated Brain Diseases

Vascular Dementia Vascular dementia is defined as the dementia resulting from ischemic, ischemic-hypoxic, or hemorrhagic brain lesions due to cerebrovascular or cardiovascular pathology. Clinical findings in vascular dementia are heterogeneous and depend to a great extent on the speed, total volume, and localization of the lesions. Typically, the onset is in later life, and the… Read More »

Subcortical Dementias

Huntington’s Disease Huntington’s disease has the three main characteristics of the subcortical dementia syndrome, together with the classic choreoathetoid movement disorder and a positive family history. Huntington’s disease usually has its onset in the third or fourth decade, although juvenile forms occasionally occur. The psychopathology, both cognitive and noncognitive, may appear before the movement abnormalities.… Read More »

Cortical Dementias

Alzheimer’s Disease Most cases of Alzheimer’s disease start after age 65, but an earlier onset is not infrequent. Although some authors consider “presenile” and “senile” clinical forms to be different diseases, most consider them the same disorder with varied age at onset. The characteristic general dementia syndrome has been described and includes the cortical signs… Read More »