Tag Archives: Candesartan

Pharmacological Treatment of Dementia

General guidelines for psychotropic medication use in frail elderly patients are applicable. Systematic evidence to support the effectiveness of particular psychotropic drugs in dementia patients is limited. Therefore, choice of drug class may be based on clinical evidence, and choice of agent is often based on the side-effect profile and on the characteristics of a… Read More »

Specific Migraine-Preventive Agents: Other Drugs

Alpha Antagonists The U.S. Headache Consortium Guidelines and the AHCPR Technical Review included 17 controlled trials of a2 agonists for the prevention of migraine: 16 of clonidine () and one of guanfacine. The evidence from these trials suggests that a2 agonists are minimally, and not conclusively, efficacious. Of the 11 placebo-controlled trials of clonidine, 3… Read More »

The drugs used for blood pressure control and headache prevention

The following medications are used for blood pressure control and headache prevention. Match each with it mechanism of action. Use each answer once, more than once, or not at all. A. Lisinopril (Prinivil, Zestril) B. Candesartan (Atacand) C. Atenolol (Tenormin) D. Verapamil (Calan) E. Clonidine (Catapres) 1. a2 Agonists 2. Angiotensin II receptor blocker 3.… Read More »

Which drugs is most likely to lead to overt hypothyroidism?

Which medication, when given to patients with preexisting treated hypo-thyroidism, is most likely to lead to overt hypothyroidism? A. Lamotrigine (Lamictal) B. Carbamazepine (Tegretol) C. Phenytoin (Dilantin) D. Divalproex sodium (Depakote) E. Gabapentin (Neurontin) The answer is B. Enzyme-inducing antiepilepsy medications, including carbamazepine (Tegretol) and oxcarbazepine (Trileptal), can reduce serum thyroid hormone concentrations through increased… Read More »