Tag Archives: Celexa

Alzheimer’s Disease Therapies

Current Therapies for Alzheimer’s Disease Because there is currently no cure for Alzheimer’s disease (), the primary goal of treatment remains the relief of cognitive, functional, and behavioral symptoms associated with the disease. Hence, current therapies aim to improve the quality of life for both Alzheimer’s disease patients and the caregivers who often must cope… Read More »

Alzheimer’s Therapy: Antidepressants

Overview. Major depression affects approximately 15% of Alzheimer’s disease patients. By comparison, 5-12% of the general population aged 15 years or older in the major pharmaceutical markets experience at least one episode of major depression per year. Because depression itself may lead to declines in cognition and function, treatment of depression in Alzheimer’s disease patients… Read More »

How is menopause likely to affect my ADHD symptoms?

As you enter your late 40s and early 50s, it is important that you become aware of several perimenopausal and menopausal issues that affect women, but especially those with attention-deficit/hyperactivity disorder. First, menopause comes with a whole host of symptoms, including memory problems and mood changes, in addition to hot flashes, insomnia, and other physical… Read More »

Minor Depression

Etiology and Pathophysiology Minor depression is only a proposed diagnosis in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, and there are no International Classification of Diseases codes to categorize it. The proposed diagnostic category for minor depression in Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition describes a depressive disorder that… Read More »

Minor Depression: Escitalopram, Paroxetine, Sertraline, and Fluoxetine

Selective Serotonin Reuptake Inhibitors The seven available agents in the selective serotonin reuptake inhibitor class are citalopram (Lund-beck’s Cipramil, Forest Laboratories’ Celexa, generics) and its single enan-tiomer, escitalopram (Lundbeck’s Cipralex, Forest’s Lexapro); paroxetine (GSK’s Paxil/Seroxat, Novartis’s Frosinor, generics); the controlled-release version of paroxetine (GSK’s Paxil CR); sertraline (Pfizer’s Zoloft); fluoxetine (Eli Lilly’s Prozac, generics); and… Read More »

Chronic Illness: Current Therapies

The main goal of bipolar disorder drug treatment is to establish euthymia (stable mood with a persistent sense of well-being) without inducing mania or rapid cycling (i.e., four or more mood episodes in a 12-month period). For this reason, drug treatment usually consists of an agent or, more frequently, combinations of agents that exert both… Read More »

Uses of Citalopram for OCD

Use in Children and Adolescents There have been some reports of efficacy of citalopram in children. Maud and Stein (1996) described one case of a prepubertal girl with obsessive-compulsive disorder who responded to 40 mg citalopram within 10 weeks and remained well for an additional 3 months thereafter. More significant is an open-label trial of… Read More »

Side Effects of Citalopram

Like the other SSRIs, citalopram is very well tolerated in general. It has a side effect profile markedly different from the older TCAs in that it is generally lacking significant anticholinergic effects. The most commonly reported adverse events (in comparison with placebo) include nausea (8% versus placebo), dry mouth (7.4%), somnolence (7.6%), increased sweating (3.9%),… Read More »

Doses of Citalopram for OCD

Most patients easily tolerate an initial dose of 20 mg, administered once daily. This dose can be taken in the morning or at night depending on the individual’s side effect profile, because some patients may develop insomnia or other sleep disturbance in contrast to the more commonly reported somnolence. It is not necessary to take… Read More »

Citalopram: History of Use in OCD

Citalopram has been subjected to extensive investigation in depression over the past decade. It has been repeatedly shown to be significantly better than placebo (). Citalopram has also been compared extensively with numerous other antidepressants, including the tricyclic compounds imipramine and clomipramine and the SSRIs fluoxetine, fluvoxamine, and sertraline, and has been found to have… Read More »