Tag Archives: Clarithromycin

Treatment of the epilepsy patient with hepatic disease

The liver is the principal organ of drug metabolism. Some drugs are absorbed from the gut, delivered to the liver and undergo first-pass metabolism prior to reaching the systemic circulation. Metabolism of these drugs is significantly affected by hepatic vascular supply; if hepatic blood flow is reduced, first-pass metabolism is decreased and more drug reaches… Read More »

Tenprolide (Quetiapine) 50mg, 200mg, 300mg and 400mg Tablets

Quetiapine What Tenprolide tablets are and what they are used for Tenprolide tablets contains a substance called quetiapine and belongs to a group of medicines called antipsychotics. Tenprolide tablets are prolonged-release tablets which means that the active ingredients is released slowly from the tablet so that you only have to take them once a day.… Read More »

Caffeine-ergotamine combination…

A 50-year-old man noted 3 days of right leg pain that increased while walking. On examination, his right leg was cool and pale. He had been taking a caffeine-ergotamine combination preparation for several years for chronic headaches. As an astute clinician, you suspect a drug interaction. Which of his other medications is the probable culprit?… Read More »

Side Effects of Mood Stabilizers and Atypical Antipsychotics

This post provides an overview of developmental issues related to side effects, and then reviews the most common adverse events and concerns related to mood stabilizers and atypical antipsychotics. There are clear developmental differences in adverse event expression or side effects risks when mood stabilizers and antipsychotics are used in children and adolescents. All the… Read More »

Atypical Antipsychotics

Atypical Antipsychotics: Side Effects A number of typical and atypical antipsychotics increase the QTc interval and augment the risk for torsade de pointes (torsades des pointes) and ventricular arrhythmias. Cardiovascular Risk QT relates to the time lapse from the beginning of the QRS until the end of the T-wave; this corresponds to the ventricular systole.… Read More »