Tag Archives: Demerol

Delirium (Acute Confusional State)

Description of Medical Condition Delirium is a neurologic complication of illness and/or medication use that is especially common in older patients. The key diagnostic features are an acute change in mental status that fluctuates, abnormal attention, and either disorganized thinking or altered level of consciousness. Delirium is a medical emergency requiring immediate evaluation in order… Read More »

Opioid Narcotics

Opium poppies can be seen in Greek drawings and on coins that antedate written Greek literature by at least one thousand years. Homer and Hesiod wrote of the medicinal effects of poppies that symbolized sleep, even death. The standard agent for euthanasia and suicide, which was given to Socrates, was a mixture of hemlock and… Read More »

Weak Opiates

• Codeine — has a weak affinity to mu opioid receptors; it is about 15% as potent as morphine (the opiate “gold standard”). It has a 2.5 to 3 hour half-life; major side effects include constipation and nausea; dosages greater than 65 mg every four to six hours are not appropriate. • Hydrocodone (Vicodin, Vicoprofen,… Read More »

Monoamine Oxidase Inhibitor

Monoamine oxidase (MAO) inhibitors are one of the two oldest classes of antidepressants, having been discovered to have antidepressant properties in the early 1950s. After the development of agents that were less toxic than the first monoamine oxidase inhibitor (iproniazid), they were second-line agents after the tricyclics. However, over the last 20 years, with the… Read More »