Tag Archives: Dextromethorphan

Pharmacological Treatment of Pain

While medications are often prescribed for all types of chronic pain, research has consistently shown that several classes have proven efficacy for the treatment of neuropathic pain. Ideally, pharmacotherapy of pain would be specifically selected on the basis of considerations of etiology (e.g., ischemic, neuropathic), pathophysiology (e.g., demyelination, central pain), and anatomy (e.g., C fibers,… Read More »

Ketamine And Other NMDA Antagonists

Ketamine is an anaesthetic drug with a few notable features which have resulted in its introduction to pain clinic practice. The rationale for its use is supported by animal studies which allow tentative conclusions to be drawn about a mechanism of action. However, the extrapolation of animal data, based on electrophysiological and behavioural studies, to… Read More »

Matching SSRI to Depressive Subtype

Atypical Depression Atypical depression is characterized by mood reactivity and two of the following: weight or appetite increase, hypersomnia, leaden paralysis and a pattern of interpersonal rejection sensitivity. MAOIs have been found to be superior to TCAs for atypical depression but recent views are that SSRIs are also an effective treatment for this subtype. Response… Read More »

Sertraline 50 mg & 100 mg Tablets

Generic name: Sertraline Sertraline 50 mg Film coated Tablets Sertraline 100 mg Film coated Tablets 1. What Sertraline Tablets is and what it is used for Sertraline Tablets contains the active substance sertraline and are used to treat depression (major depressive episodes). Sertraline belongs to a group of antidepressant drugs called Selective Serotonin Re-uptake inhibitors.… Read More »

Drugs for Treatment of Chronic Pain

The purpose of this post is to go over the various types of medications that can be used for the treatment of pain. Many of the medications have been discussed previously, but this post attempts to consolidate these various medications. There are two more pain states that need to be discussed: chronic pain, which persists… Read More »

Monoamine Oxidase Inhibitor

Monoamine oxidase (MAO) inhibitors are one of the two oldest classes of antidepressants, having been discovered to have antidepressant properties in the early 1950s. After the development of agents that were less toxic than the first monoamine oxidase inhibitor (iproniazid), they were second-line agents after the tricyclics. However, over the last 20 years, with the… Read More »