Tag Archives: Fluoxetine

Pharmacological Treatment of Dementia

General guidelines for psychotropic medication use in frail elderly patients are applicable. Systematic evidence to support the effectiveness of particular psychotropic drugs in dementia patients is limited. Therefore, choice of drug class may be based on clinical evidence, and choice of agent is often based on the side-effect profile and on the characteristics of a… Read More »

Alzheimer’s Therapy: Antidepressants

Overview. Major depression affects approximately 15% of Alzheimer’s disease patients. By comparison, 5-12% of the general population aged 15 years or older in the major pharmaceutical markets experience at least one episode of major depression per year. Because depression itself may lead to declines in cognition and function, treatment of depression in Alzheimer’s disease patients… Read More »

Pharmacotherapy of Adult ADHD

Originally conceptualized as a disorder of childhood (), attention deficit hyperactivity disorder (ADHD) is increasingly recognized in adults. attention deficit hyperactivity disorder is estimated to affect 2-9% of school-age children and up to 5% of adults (). Although some investigators question the persistence of attention deficit hyperactivity disorder in adulthood (), long-term controlled follow-up studies… Read More »

Management of Bipolar Disorder

Antipsychotics are frequently used in the treatment of bipolar disorder. Most patients started on antipsychotics as adjunctive treatment for manic episodes continue these agents beyond 6 months, even in the absence of conclusive data on the long-term efficacy of most antipsychotics in maintenance treatment. Typical antipsychotics are effective antimanic agents but appear less effective than… Read More »

Bipolar Depression

The notion that bipolar and unipolar depression might be distinct illnesses was first proposed in the middle of the 20th century. Before this time, manic-depressive illness was considered to encompass a broad range of psychopathology, including recurrent unipolar depression. We now recognize that there are substantial differences between depression arising from bipolar disorder and with… Read More »

Bipolar Depression: Treatment Acute Pharmacotherapy

Lithium For many years, lithium was considered to be the standard treatment for bipolar depression. Improvement rates of 80% have been reported in nine placebo-controlled studies, conducted mostly in the 1970s. Response rates for lithium were equivalent to those for tricyclic antidepressants (tricyclic antidepressants). A recent study of outpatients with bipolar depression compared the efficacy… Read More »

Sedating Antidepressants

Given the high comorbidity of insomnia and depression and / or anxiety, sedating antidepressants have considerable relevance for treating insomnia. (Note: Sedating antidepressants can effectively treat both depressive and anxious symptoms.) The sleep-promoting properties of the sedating antidepressants, as well as their lack of abuse potential or propensity to induce tolerance, make these agents viable… Read More »

Treatment of Social Anxiety Disorder

Current recommended treatment options for social anxiety disorder include pharmacotherapy and cognitive behavioural therapy (CBT). Although several randomised controlled trials (RCTs) have failed to show efficacy for beta-adrenoceptor antagonists in generalised social anxiety disorder (SAD), it has been suggested that these agents may be useful in non-generalised social anxiety disorder (SAD), patients with performance anxiety… Read More »

Treating Anxiety Disorders In Adults

Anxiety is an emotional and physiological state that all people feel and that can be either normal or pathological. Anxiety can be defined as a feeling of unpleasant apprehension typically accompanied by bodily sensations such as a tightness in the chest, a feeling of choking, perspiring, and trembling or shaking. Often, anxious individuals feel restless… Read More »

Treatment of Anxiety in the Medically Ill

Psychotherapy An overemphasis on psychopharmacology in the care of medically ill patients may result in overlooking the value of psychotherapy. The first step in the treatment of anxiety is to spend time listening to and talking with the patient. Just as in psychotherapy with any patient, empathic listening is a powerful tool to relieve distress.… Read More »