Tag Archives: Imitrex

Which of the triptans is available in more than one drug delivery formulation?

Which of the triptans listed is available in more than one medication delivery formulation? A. Almotriptan (Axert) B. Rizatriptan (Maxalt) C. Frovatriptan (Frova) D. Naratriptan (Amerge) E. Eletriptan (Relpax) The answer is B. Multiple formulations are currently available for sumatriptan (Imitrex; subcutaneous injection, swallowed tablet, intranasal spray), zolmitriptan (Zomig; swallowed tablet, orally dissolving tablet, intranasal… Read More »

Which of the triptans to have the lowest incidence of chest discomfort?

Which of the following triptans appears to have the lowest incidence of chest discomfort? A. Almotriptan (Axert) B. Subcutaneous sumatriptan (Imitrex) C. Intranasal zolmitriptan (Zomig) D. Oral sumatriptan (Imitrex) E. Eletriptan (Relpax) The answer is A. Chest discomfort, presumably related to pulmonary vasoconstriction and/or esophageal spasm, is lowest in oral triptan formulations. The tolerability of… Read More »

Risk of which is not increased in patients with migraine headaches?

Risk of which of the following is not increased in patients with migraine headaches? A. Arterial dissection B. Subarachnoid hemorrhage (SAH) C. Ischemic stroke D. Myocardial infarct (MI) E. All of the above The answer is B. An association exists between migraine and ischemic cardiovascular and cerebrovascular events, but migraine is not a risk factor… Read More »

Match the triptan with its specific characteristic…

Match the triptan with its specific characteristic. Use each answer only once. A. Sumatriptan (Imitrex) B. Frovatriptan (Frova) C. Naratriptan (Amerge) D. Almotriptan (Axert) E. Rizatriptan (Maxalt) 1. Highest oral bioavailability 2. Lowest oral bioavailability 3. Longest half-life 4. Second longest half-life 5. Shortest time to maximum blood concentration The answer is A 2, B… Read More »

Which triptan is associated with the lowest headache recurrence rate after acute migraine treatment?

Which triptan is associated with the lowest headache recurrence rate after acute migraine treatment? A. Sumatriptan (Imitrex) B. Rizatriptan (Maxalt) C. Frovatriptan (Frova) D. Almotriptan (Axert) E. Naratriptan (Amerge) The answer is C. Frovatriptan (Frova) is a potent 5-HT 1D receptor agonist and has the highest 5-HT1B potency in the triptan class. Frovatriptan has the… Read More »

The nonprescription migraine combination drugs…

The nonprescription migraine combination medication acetaminophen / aspirin /caffeine: A. Was found possibly superior to sumatriptan (Imitrex) in a head-to-head comparison in acute migraine. B. Is more likely to cause medication overuse headache (MOH) than a triptan. C. Causes a less intractable MOH than a triptan. D. Appears to be less effective than ibuprofen in… Read More »

Headaches and sleep

Which of the following statements best describes headaches and sleep? A. Snoring is correlated with frequent morning headaches. B. The use of continuous positive pressure airway pressure (CPAP) in patients with obstructive sleep apnea (OSA) does not improve frequent morning headaches. C. Gender predilection for OSA mirrors gender predilection for migraine headaches. D. Obstructive sleep… Read More »

Which of the drugs effective and well tolerated in the treatment of adolescent migraine?

Which of the following has been shown to be effective and well tolerated in the treatment of adolescent migraine? A. Intranasal zolmitriptan (Zomig) B. Subcutaneous sumatriptan (Imitrex) C. Oral frovatriptan (Frova) D. Butalbital/aspirin/caffeine combination E. All of the above The answer is A. The intranasal triptans, sumatriptan (Imitrex) and zol-mitriptan (Zomig), are particularly suitable to… Read More »

Which of the short-acting triptans has been shown to prevent menstrual migraine?

Which of the following short-acting triptans has been shown to prevent menstrual migraine in a large, randomized, placebo-controlled trial? A. Zolmitriptan (Zomig) B. Eletriptan (Relpax) C. Sumatriptan (Imitrex) D. Rizatriptan (Maxalt) E. None of the above The answer is A. Currently, no triptan is FDA approved for the short-term, peri-menstrual prevention of menstrual migraine. However,… Read More »

Which of the drug of choice for abortive treatment of a CH?

Which of the following is the drug of choice for abortive treatment of a CH? A. Rectal ergotamine B. Subcutaneous sumatriptan (Imitrex) C. Intranasal zolmitriptan (Zomig) D. Sublingual rizatriptan (Maxalt) E. Oral sumatriptan The answer is B. The pain of a cluster headaches generally lasts 15 to 180 minutes. Because of the CH’s rapid build-up… Read More »