Tag Archives: Indocin

Which drug has shown benefit in treating SUNCT?

Which medication has shown benefit in treating SUNCT and short-lasting unilateral neuralgiform headache attacks with cranial autonomic symptoms (SUNA)? A. Lamotrigine (Lamictal) B. Gabapentin (Neurontin) C. Topiramate (Topamax) D. Lidocaine E. All of the above The answer is E. SUNCT and SUNA are primary headache syndromes, classified as TACs, and associated with hypothalamic activation. They… Read More »

Which of the drugs be used to treat patients with headaches associated with sexual activity?

Which of the following can be used to treat patients with headaches associated with sexual activity? A. Indomethacin (Indocin) B. β-Blockers C. Short half-life triptans D. Long half-life triptans E. All of the above The answer is E. Benign headaches associated with sexual activity are either a dull aching pain prior to orgasm or a… Read More »

Which of the drugs effective in treating patients with SUNCT?

Which of the following has been shown to be effective in treating patients with SUNCT? A. Intranasal zolmitriptan (Zomig) B. Inhalational oxygen C. Intramuscular Indomethacin (Indocin) D. Intravenous (IV) lidocaine E. Oral Ketoralac (Toradol) The answer is D. As distinct from PH and hemicrania continua, SUNCT/ SUNA does not respond to indomethacin (Indocin). Although CHs… Read More »

Patients with primary cough headache often respond to treatment with which drug?

Patients with primary cough headache most often respond to prophylactic treatment with which medication? A. Lithium B. Indomethacin (Indocin) C. Verapamil (Calan) D. Lamotrigine (Lamictal) E. Gabapentin (Neurontin) The answer is B. Primary cough headache generally responds to preventa-tive treatment with indomethacin (Indocin) at doses ranging from 25 to 150 mg daily. The pathophysiologic mechanism… Read More »

Which preventative drug gives the most rapid relief of CH?

Which preventative medication gives the most rapid relief of CH? A. Verapamil (Calan) B. Lithium C. Indomethacin (Indocin) D. Corticosteroids E. Gabapentin (Neurontin) The answer is D. Although verapamil (Calan) is the preventative drug of choice in patients with CHs, it may require escalation of the dose over time to be effective. Likewise, lithium needs… Read More »

Most effective in preventing attacks of short-lasting unilateral neuralgiform headache attacks…

Which of the following oral agents has been shown to be most effective in preventing attacks of short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT)? A. Gabapentin (Neurontin) B. Indomethacin (Indocin) C. Carbamazepine (Tegretol) D. Lamotrigine (Lamictal) E. Pregabalin (Lyrica) The answer is D. SUNCT/SUNA is particularly refractory to prevention with oral… Read More »

Preventative treatment with indomethacin (Indocin)

Which of the following primary headache disorders characteristically responds to preventative treatment with indomethacin (Indocin)? A. Paroxysmal hemicrania (PH) B. Short-lasting unilateral neuralgiform headache attacks with cranial auto-nomic symptoms (SUNA) C. SUNCTC D. Cluster headache (CH) E. Migraine without aura The answer is A. Paroxysmal hemicrania responds dramatically to prevention with indomethacin (Indocin), distinguishing it… Read More »

Match the cause of episodic unilateral facial pain…

Match the cause of episodic unilateral facial pain with its most effective preventative pharmacologic therapy. Each answer may be used once, more than once, or not at all. A. Cluster headache (CH) B. Paroxysmal hemicrania (PH) C. Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) D. Trigeminal neuralgia E. Hemicrania continua 1. Lamotrigine… Read More »

Which medication is the preventative drug of choice for chronic cluster headache?

Which medication is the preventative drug of choice for both episodic and chronic cluster headache (CHs)? A. Verapamil (Calan) B. Lithium C. Indomethacin (Indocin) D. Lamotrigine (Lamictal) E. Gabapentin (Neurontin) The answer is A. Because the pain of a cluster headache (CH) is both excruciating and difficult to treat acutely, finding an effective preventative medication… Read More »

Nonsteroidal Anti-Inflammatory Drugs

NSAIDs (Nonsteroidal Anti-Inflammatory Drugs) are anti-inflammatory, analgesic, and antipyretic agents. They decrease prostaglandin production by inhibiting COS (COX-1 and 2) enzymes. They are the drugs of choice for use in osteoarthritis (OA) and rheumatoid arthritis for pain. There are over 20 different nonsteroidal anti-inflammatory drugs available in the United States in ten different chemical classes:… Read More »