Tag Archives: Lithium carbonate

Information about Bipolar Disorder for Patients and Families

Bipolar disorder, also called manic-depressive disorder, is a recurrent illness in which the individual’s mood cycles between depression and mania with periods of normality. The illness is a mood disorder. The individual’s moods may swing from manic euphoria, with boundless energy in pursuit of grandiose plans, to depths of depression, with feelings of despair and… Read More »

Dissociative [Conversion] Disorders

Description of Medical Condition A sudden change in state of consciousness, identity, motor behavior, thoughts, feelings and perception of external reality to such an extent that these functions do not operate congruently. Many pathologic symptoms can be found, but the patient experiences dysphoria, suffering, and maladaptive functioning. Disorders include: • Dissociative amnesia • Dissociative fugue… Read More »

Personality Disorders

Description of Medical Condition A group of conditions, with onset at or before adolescence, characterized by enduring patterns of maladaptive and dysfunctional behavior that deviate markedly from one’s culture and social environment leading to functional impairment and distress to the individual, coworkers and the family. These behaviors are perceived by the patient to be “normal”… Read More »

Fluvoxamine: History of Use in OCD

Fluvoxamine was originally developed in Europe as an antidepressant. In most published double-blind trials in patients with depression, fluvoxamine has been shown to be significantly better than placebo and to be equal in efficacy to both TCAs and other SSRIs. Studies were also conducted with fluvoxamine in patients with obsessive-compulsive disorder on the basis of… Read More »

Pharmacotherapy and psychotherapy for TR-PTSD

TR-PTSD: Treatment Resistant Posttraumatic Stress Disorder After treatment-resistance is determined, there are several proposed pharmacotherapuetic and psychotherapeutic approaches. Though the literature base is small, several randomized controlled trials (RCTs), open-label trials and case series exist that evaluate the efficacy of alternative treatments. As noted above, the criteria for response can be based on the CAPS… Read More »

Treating Bipolar Disorder in Children and Adolescents

Mood stabilizers The mood stablizers (lithium, carbamazepine, sodium valproate) have shown proven efficacy in the treatment of children with manic or hypomanic symptoms. They have also been proven as maintenance treatments for bipolar disorder. Their use as augmentation medications for cases of resistant depression is based on the adult literature. Lithium Lithium remains the mainstay… Read More »

Medications for Anxiety Disorders

Drugs, such as alcohol and opiates, have been used to treat the symptoms of anxiety for centuries. Today, anxiety disorders are treated by specific antianxiety drugs and by antidepressants. People with panic disorders have been effectively treated with tricyclic antidepressants such as desipramine (Norpramine), clomipramine (Anafranil), or imipramine (Tofranil); MAO inhibitors (MAOIs) such as phenelzine… Read More »

Predictors Of Lithium Response And Nonresponse

Although studies reviewed thus far support the efficacy of lithium treatment for acute mania, the presence of concurrent depression or depressive symptoms during mania, the so-called mixed state, has been associated with poor lithium response. Himmelhoch et al. observed that patients with mixed states were significantly less likely to demonstrate a good treatment response than… Read More »

Predictors Of Valproate Response And Nonresponse

In contrast with lithium, valproate has been associated with a good antimanic response in patients with concurrent depressive symptoms or syndromes. Calabrese and colleagues have reported favorable responses in patients with rapid-cycling bipolar disorder with index episodes of either mixed or pure mania who received open-label valproate alone or in combination with other psychotropic medication.… Read More »