Tag Archives: Methadone

Restless Legs Syndrome and Periodic Limb Movements

Patients with restless legs syndrome describe subjective discomfort of the lower extremities that worsens at night. Patients can have an irresistible need to move their legs in bed or during prolonged periods of sedentary activity, such as airplane flights. This condition was first described by Ekblom in 1945. As a result of these distressing symptoms,… Read More »

Pharmacological Treatment of Pain

While medications are often prescribed for all types of chronic pain, research has consistently shown that several classes have proven efficacy for the treatment of neuropathic pain. Ideally, pharmacotherapy of pain would be specifically selected on the basis of considerations of etiology (e.g., ischemic, neuropathic), pathophysiology (e.g., demyelination, central pain), and anatomy (e.g., C fibers,… Read More »

Tenprolide (Quetiapine) 50mg, 200mg, 300mg and 400mg Tablets

Quetiapine What Tenprolide tablets are and what they are used for Tenprolide tablets contains a substance called quetiapine and belongs to a group of medicines called antipsychotics. Tenprolide tablets are prolonged-release tablets which means that the active ingredients is released slowly from the tablet so that you only have to take them once a day.… Read More »

Opioids In Chronic Pain

The use of opioids in pain of non-malignant origin is controversial and depends on a proper understanding of the nature of chronic pain, and the strategy of its management. Patients with chronic pain who take opioids must understand the rationale for the use and be prepared to be an active partner in the management of… Read More »

Ketamine And Other NMDA Antagonists

Ketamine is an anaesthetic drug with a few notable features which have resulted in its introduction to pain clinic practice. The rationale for its use is supported by animal studies which allow tentative conclusions to be drawn about a mechanism of action. However, the extrapolation of animal data, based on electrophysiological and behavioural studies, to… Read More »

Substance-Related Disorders

Substance abuse is a major social and public health problem that affects millions of Americans and their families. It occurs in all social classes, at all professional levels, and in most cultural and ethnic groups, and it can be comorbid with a variety of mental disorders. Social problems that occur as a result of substance… Read More »

Opioid Narcotics

Opium poppies can be seen in Greek drawings and on coins that antedate written Greek literature by at least one thousand years. Homer and Hesiod wrote of the medicinal effects of poppies that symbolized sleep, even death. The standard agent for euthanasia and suicide, which was given to Socrates, was a mixture of hemlock and… Read More »

Substance-Related Disorders: Intervention

The cocaine and crack epidemic of the 1980s challenged traditional alcohol and drug treatment programs, because it resulted in a significant number of people being addicted not only to cocaine or crack but also to alcohol. It pointed out the failure of a system that separates alcoholism and chemical dependency, and it increased the importance… Read More »

Pharmacological Treatment Of Restless Legs Syndrome

Dopaminergic Agents in the Treatment Of Restless Legs Syndrome Levodopa was the first dopaminergic agent found effective in restless legs syndrome and has since shown evidence of efficacy in controlled trials. Benes et al. found improved quality of sleep, reduced sleep latency, and better quality of life with levodopa / benserazide given in a single… Read More »