Tag Archives: Metronidazole

Bacterial Meningitis: Antimicrobial Therapy

The initial management of the patient with suspected acute bacterial meningitis is empiric antimicrobial and adjunctive therapy begun immediately after obtaining blood for bacterial culture. Respiratory isolation for the first 24 hours of antimicrobial therapy is recommended only for patients with suspected meningococcal meningitis. Respiratory isolation is not required for patients with meningitis due to… Read More »

Treatment of the epilepsy patient with hepatic disease

The liver is the principal organ of drug metabolism. Some drugs are absorbed from the gut, delivered to the liver and undergo first-pass metabolism prior to reaching the systemic circulation. Metabolism of these drugs is significantly affected by hepatic vascular supply; if hepatic blood flow is reduced, first-pass metabolism is decreased and more drug reaches… Read More »

Delirium: Etiology

Delirium has a wide variety of etiologies, which may occur alone or in combination (). These include primary cerebral disorders, systemic disturbances that affect cerebral function, drug and toxin exposure (including intoxication and withdrawal), and a range of factors that can contribute to delirium but have an uncertain role as etiological factors by themselves (psychological… Read More »

Empiric Antimicrobial Therapy For Bacterial Brain Abscess

As stated above, the bacteria found in brain abscesses correspond to predisposing conditions such as pathogenesis of infection, host immunity, or events leading to direct inoculation. These predisposing conditions must be considered when designing an empiric antimicrobial regimen for patients with brain abscesses. Table Empiric antimicrobial therapy for brain abscess delineates a number of predisposing… Read More »

Principles of management

The management of major depressive disorder (major depressive disorder) involves establishing a correct diagnosis and applying evidence based and goal directed principles of treatment. These treatment principles include recognizing and treating any coexisting medical conditions, building a therapeutic alliance with patients and choosing an appropriate treatment, as well as monitoring and maintaining response (Table Nine… Read More »

Side Effects of Mood Stabilizers and Atypical Antipsychotics

This post provides an overview of developmental issues related to side effects, and then reviews the most common adverse events and concerns related to mood stabilizers and atypical antipsychotics. There are clear developmental differences in adverse event expression or side effects risks when mood stabilizers and antipsychotics are used in children and adolescents. All the… Read More »

Adverse Effects Of Lithium Treatment

Lithium has a potential to induce a score of adverse effects. In the literature, lithium treatment has often been associated with many side effects and toxicity, because it may exert many well-documented impacts on the biology of the human body. Therefore, it can, depending on the circumstances, lead to a number of adversities: neurological, cardiovascular,… Read More »