Tag Archives: Moclobemide

Nonstimulant medications in the treatment of adults with ADHD

Here are some important points regarding nonstimulants in the treatment of adults with ADHD. Tricyclic antidepressants and bupropion are second-line therapies. Antidepressant dosing of the agents appears necessary for attention deficit hyperactivity disorder efficacy. Serotonergic medications do not appear effective in the treatment of core attention deficit hyperactivity disorder symptoms but may be useful for… Read More »

Social Anxiety Disorder

Epidemiology of Social Anxiety Disorder (SAD) SAD (social anxiety disorder) (social anxiety disorder), also known as social phobia, is characterised by excessive fear of embarrassment or humiliation in social situations, which in turn leads to marked distress or avoidance of these situations and functional impairment as described in DSM-IV-TR. It is a common disorder with… Read More »

Treatment of Social Anxiety Disorder

Current recommended treatment options for social anxiety disorder include pharmacotherapy and cognitive behavioural therapy (CBT). Although several randomised controlled trials (RCTs) have failed to show efficacy for beta-adrenoceptor antagonists in generalised social anxiety disorder (SAD), it has been suggested that these agents may be useful in non-generalised social anxiety disorder (SAD), patients with performance anxiety… Read More »

Personality and Treatment

Help-Seeking Behavior and Illness Detection Only a minority of people who have a diagnosable mental disorder receive professional help. This has been repeatedly shown across major epidemiological surveys (). In both the European Depression Epidemiological Survey (DEPRES) () and in the Ontario Health Survey (), fewer than 50% of detected cases of major depressive disorder… Read More »

Minor Depression

Etiology and Pathophysiology Minor depression is only a proposed diagnosis in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, and there are no International Classification of Diseases codes to categorize it. The proposed diagnostic category for minor depression in Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition describes a depressive disorder that… Read More »

Minor Depression: Escitalopram, Paroxetine, Sertraline, and Fluoxetine

Selective Serotonin Reuptake Inhibitors The seven available agents in the selective serotonin reuptake inhibitor class are citalopram (Lund-beck’s Cipramil, Forest Laboratories’ Celexa, generics) and its single enan-tiomer, escitalopram (Lundbeck’s Cipralex, Forest’s Lexapro); paroxetine (GSK’s Paxil/Seroxat, Novartis’s Frosinor, generics); the controlled-release version of paroxetine (GSK’s Paxil CR); sertraline (Pfizer’s Zoloft); fluoxetine (Eli Lilly’s Prozac, generics); and… Read More »

Side Effects of Citalopram

Like the other SSRIs, citalopram is very well tolerated in general. It has a side effect profile markedly different from the older TCAs in that it is generally lacking significant anticholinergic effects. The most commonly reported adverse events (in comparison with placebo) include nausea (8% versus placebo), dry mouth (7.4%), somnolence (7.6%), increased sweating (3.9%),… Read More »

Treatments for Social Phobia

Social phobia was first described as a unique, diagnosable disorder in DSM-III (American Psychiatric Association 1980). From a historical perspective, the disorder has been recognized since the middle of the 19th century, when Casper described erythrophobia (Casper 1902). Marks (1970) separated social phobia from other types of anxiety, including agoraphobia and simple phobia; thus, he… Read More »

Drug treatment of elderly patients with depression

There is a consensus that antidepressant therapy is effective and should be recommended for the treatment of depression in the elderly. Because of the pharmacokinetic changes in the elderly, the tolerability of antidepressants, especially of the classic tricyclics, is reduced compared with younger populations. However, this problem can be managed by a careful dosing regime… Read More »

Treatment for Social Phobia

Management Effective pharmacological and psychological treatments of social phobia are available. At present, phenelzine is the pharmacological treatment of choice, and cognitive-behavioral group treatment is the psychological treatment of choice for the generalized subtype (). These treatments appear to be about equally effective and, when combined, may work better than either treatment alone. Evidence favoring… Read More »