Tag Archives: Olanzapine

Pharmacological Treatment of Dementia

General guidelines for psychotropic medication use in frail elderly patients are applicable. Systematic evidence to support the effectiveness of particular psychotropic drugs in dementia patients is limited. Therefore, choice of drug class may be based on clinical evidence, and choice of agent is often based on the side-effect profile and on the characteristics of a… Read More »

Alzheimer’s Therapy: Antipsychotics

Overview. Behavioral problems are prevalent in later stages of Alzheimer’s disease, when 50-60% of patients develop severe psychotic symptoms (). Behavioral symptoms range from depression and apathy to delusions, hallucinations, and aggressiveness. They are extremely distressing and burdensome to caregivers and affect both the quality of patient care and the choice of treatment. Aggressive and… Read More »

Management of Bipolar Disorder

Antipsychotics are frequently used in the treatment of bipolar disorder. Most patients started on antipsychotics as adjunctive treatment for manic episodes continue these agents beyond 6 months, even in the absence of conclusive data on the long-term efficacy of most antipsychotics in maintenance treatment. Typical antipsychotics are effective antimanic agents but appear less effective than… Read More »

Bipolar Depression

The notion that bipolar and unipolar depression might be distinct illnesses was first proposed in the middle of the 20th century. Before this time, manic-depressive illness was considered to encompass a broad range of psychopathology, including recurrent unipolar depression. We now recognize that there are substantial differences between depression arising from bipolar disorder and with… Read More »

Bipolar Depression: Treatment Acute Pharmacotherapy

Lithium For many years, lithium was considered to be the standard treatment for bipolar depression. Improvement rates of 80% have been reported in nine placebo-controlled studies, conducted mostly in the 1970s. Response rates for lithium were equivalent to those for tricyclic antidepressants (tricyclic antidepressants). A recent study of outpatients with bipolar depression compared the efficacy… Read More »

Treatment of Social Anxiety Disorder

Current recommended treatment options for social anxiety disorder include pharmacotherapy and cognitive behavioural therapy (CBT). Although several randomised controlled trials (RCTs) have failed to show efficacy for beta-adrenoceptor antagonists in generalised social anxiety disorder (SAD), it has been suggested that these agents may be useful in non-generalised social anxiety disorder (SAD), patients with performance anxiety… Read More »

What kind of medication reactions could be serious or lethal?

Concerning the medications used in the treatment of anxiety, there are several absolute red flags that any patient on those medications must know about. Please keep the following in mind: Overdose. If taken in excess — either accidental or intentional — any medication can create serious problems. In particular, however, benzodiazepines, lithium, and tricyclic antidepressants… Read More »

Treatment of Anxiety in the Medically Ill

Psychotherapy An overemphasis on psychopharmacology in the care of medically ill patients may result in overlooking the value of psychotherapy. The first step in the treatment of anxiety is to spend time listening to and talking with the patient. Just as in psychotherapy with any patient, empathic listening is a powerful tool to relieve distress.… Read More »

Schizophrenia-Negative Mode

Question. What is going on inside the mind of an adult currently suffering from schizophrenia-negative mode? Answer. It is always hard to know what is truly “going on inside the mind” of any patient, particularly patients with psychotic disorders. I am also not quite sure what you mean by “schizophrenia-negative mode,” but I assume you… Read More »