Tag Archives: Omeprazole

Treatment of the epilepsy patient with hepatic disease

The liver is the principal organ of drug metabolism. Some drugs are absorbed from the gut, delivered to the liver and undergo first-pass metabolism prior to reaching the systemic circulation. Metabolism of these drugs is significantly affected by hepatic vascular supply; if hepatic blood flow is reduced, first-pass metabolism is decreased and more drug reaches… Read More »

Citalopram 10 mg, 20 mg, 40 mg Tablets

Citalopram (si-tal-oh-pram) [Celexa] Citalopram Classification (The therapeutic classification, which categorizes drugs by the disease state they are used to treat, appears first, followed by the pharmacologic classification, which is based on the drug’s mechanism of action.) Therapeutic class: antidepressants Pharmacologic class of Citalopram: selective serotonin reuptake inhibitors (selective serotonin reuptake inhibitors (SSRIs) Pregnancy Category (pregnancy… Read More »

Matching SSRI to Depressive Subtype

Atypical Depression Atypical depression is characterized by mood reactivity and two of the following: weight or appetite increase, hypersomnia, leaden paralysis and a pattern of interpersonal rejection sensitivity. MAOIs have been found to be superior to TCAs for atypical depression but recent views are that SSRIs are also an effective treatment for this subtype. Response… Read More »

Side Effects of Mood Stabilizers and Atypical Antipsychotics

This post provides an overview of developmental issues related to side effects, and then reviews the most common adverse events and concerns related to mood stabilizers and atypical antipsychotics. There are clear developmental differences in adverse event expression or side effects risks when mood stabilizers and antipsychotics are used in children and adolescents. All the… Read More »