Tag Archives: Ondansetron

Overview of New Anxiolytics

Although the benzodiazepines have been the treatment of choice for anxiety disorders for many years, unfavorable aspects to their side-effect profile have initiated efforts to develop new-generation antianxiety agents. Over the past decade, scientists have been searching for compounds that retain the robust anxiolytic efficacy of benzodiazepines, but lack a number of unwanted properties, including… Read More »

Treatments for Social Phobia

Social phobia was first described as a unique, diagnosable disorder in DSM-III (American Psychiatric Association 1980). From a historical perspective, the disorder has been recognized since the middle of the 19th century, when Casper described erythrophobia (Casper 1902). Marks (1970) separated social phobia from other types of anxiety, including agoraphobia and simple phobia; thus, he… Read More »

Delirium: Pharmacological Treatment

Current delirium pharmacotherapies have evolved from use in the treatment of mainstream psychiatric disorders; hence, psychiatrists are well acquainted with the practicalities of their use. Medications are implicated as significant contributing factors in more than one-third of cases and can act as either protective or risk factors for delirium, depending on the drug. Pharmacological treatment… Read More »

Anxiety and Anxiety Disorders in Medical Settings

Health concerns rank with financial issues as major sources of anxiety for individuals (). Both disease states and medical settings foster such fears. Wells and colleagues () noted that 6-month and lifetime prevalence rates of anxiety disorders in patients with chronic medical conditions were 15.3% and 21.3%, respectively. These rates were significantly higher than those… Read More »

Medical Environment

For individuals in hospital settings, anxiety may be caused by the nature of the environment. The hospital setting is often a strange and frightening place (). Patients enter an unfamiliar world when they set foot in either the medical clinic or the hospital setting. One’s unique self is depersonalized when the “ticket to admission” to… Read More »

Cardiac Disease and Anxiety

Anxiety and its relation to the heart deserve special consideration given the extensive literature addressing the nature and extent of this relation. Osier’s descriptions of early-onset angina may represent the first attempt at defining what we have come to know as type A behavior (). Another early observer of the heart’s connection to anxiety was… Read More »

Management of Anxiety

Physician-Patient Relationship The physician must establish a working therapeutic alliance with any patient (). In the crisis of cancer, heart disease, or surgery, the physician is viewed as the individual who can literally save one’s life and has a unique task. This demands supportive and empathic care in both imparting information and offering hope regardless… Read More »

Pharmacotherapy of Alcohol Dependence

Disulfiram The most commonly used pharmacological adjunct for the treatment of alcohol dependence and abuse is disulfiram, or Antabuse. Disulfiram interferes with normal metabolism of alcohol, which results in an accumulation of acetaldhyde, and hence drinking following ingestion of disulfiram results in an intense physiologic reaction, characterized by flushing, rapid or irregular heartbeat, dizziness, nausea,… Read More »