Tag Archives: Pemoline

Stimulants in the treatment of adults with ADHD

Stimulant treatment of adults with attention deficit hyperactivity disorder can be characterized as follows. Stimulants represent the first-line pharamcotherapy for attention deficit hyperactivity disorder in adults. The two main types of stimulants, methylphenidate and amphetamine compounds, have different effects and are metabolized differently. Methylphenidate does not show up on urine drug screens. Stimulants are not… Read More »

Information about ADHD for Patients and Families

Attention-deficit/hyperactivity disorder (ADHD) is a common psychiatric disorder in young and school-aged children. However, it is not merely a childhood disorder. In recent years, an increasing number of adults have been diagnosed with ADHD, raising some concern that it may be overdiagnosed. Estimates of the prevalence (i.e., percentage of the population affected) of attention-deficit/hyperactivity disorder… Read More »

Antidepressant Drugs and Sexual Dysfunction

Reports of rates of sexual dysfunction in clinical populations vary widely. The main reason for such variation is the range of methods employed to collect the data. Early studies with antidepressants relied on spontaneous self-report by patients and tended to yield relatively low rates: they also failed to distinguish between rates of different forms of… Read More »

Narcolepsy: Pharmacologic Therapy

The Standards of Practice Committee of the American Academy of Sleep Medicine (AASM) provides a periodically updated list of medicines recognized for the treatments of hypersomnolence associated with narcolepsy. The list has included modafinil, amphetamines, and amphetamine-like drugs (methylphenidate), whereas sodium oxybate, non-sedating tricyclic antidepressants (TCAs, protriptyline), selective serotonin reuptake inhibitors (SSRIs, fluoxetine), and monoamine… Read More »

Adverse Effects of Treatment Drugs in Short-Term Use

Short-Term Use of Psychostimulants Psychostimulants, such as methylphenidate and dextroamphetamine, are effective in controlling the somnolence of narcolepsy. However, they often show side effects due to stimulation of the sympathetic nervous system. Constitutional factors may contribute to the development and severity of side effects. These include dry mouth, headache, palpitations, sweating, tremor, anorexia, gastritis, nausea,… Read More »

Adverse Effects of Treatment Drugs in Long-Term Use

Long-Term Adverse Effects of Psychostimulants Psychostimulants have been used for many years for the treatment of narcolepsy. Adequate control of somnolence in the daytime is usually possible. However, this control is not always possible because of side effects and nonadherence. The awakening effects of psychostimulants should not be extended beyond evening meals to minimize remaining… Read More »

Side Effects of Mood Stabilizers and Atypical Antipsychotics

This post provides an overview of developmental issues related to side effects, and then reviews the most common adverse events and concerns related to mood stabilizers and atypical antipsychotics. There are clear developmental differences in adverse event expression or side effects risks when mood stabilizers and antipsychotics are used in children and adolescents. All the… Read More »

Developmental Aspects Of Psychotropic Side Effects

Adverse events (adverse event) are developmentally sensitive. Substantial adverse event data are available for adults, but it is unknown whether adverse event risks or patterns of risk are similar in children and adolescents. Age and developmental stage can play an important role in determining adverse event patterns to pharmacological interventions. Thus, Reyes syndrome (secondary to… Read More »