Tag Archives: Phenothiazines

Drug Treatment Of Mania

When assessing the patient, enquiries should be made about their recent compliance with medication, as sudden discontinuation of lithium may have triggered the manic episode. It is usually prudent to cease any antidepressant medication they may have been taking. A physical examination and tests of the blood and urine should, if possible, precede drug treatment… Read More »

Pharmacotherapy in the Treatment of People With Schizophrenia

The pharmacological agents most primarily associated with treatment of schizophrenia are grouped in a large and heterogeneous family, the antipsychotics. Recently, this family has been subdivided into the typicals, or neuroleptics, and the atypicals (see Tables Selected Typical Antipsychotic Drugs and Their Characteristics and Atypical Antipsychotics: Relative Potencies and Side Effects). The neuroleptics are so… Read More »

Neuroleptic treatment of schizophrenia in the elderly

Neuroleptics are commonly used to treat schizophrenia and also exogenic psychosis in elderly patients (). However, there are extremely few methodologically sound controlled trials of neuroleptic drugs in this population, especially of functional psychosis (). Clinical experience and case reports indicate that the efficacy proven in younger schizophrenic patients may be extrapolated to elderly psychotic… Read More »

Delirium: Etiology

Delirium has a wide variety of etiologies, which may occur alone or in combination (). These include primary cerebral disorders, systemic disturbances that affect cerebral function, drug and toxin exposure (including intoxication and withdrawal), and a range of factors that can contribute to delirium but have an uncertain role as etiological factors by themselves (psychological… Read More »

Sleep-Related Leg Cramps

Demographics Age of Onset Sleep-related leg cramps affect all age groups, but they tend to occur more in middle-aged and older populations. In one study, the mean age of onset of cramps was 60 years; for both males and females (). Leung et al. found that no sleep-related leg cramps were reported in children younger… Read More »

Fluoxetine 10 mg, 20 mg, 40 mg Capsules

Fluoxetine (floo-ox-uh-teen) [Prozac, Prozac Weekly, Sarafem] Fluoxetine Classification (The therapeutic classification, which categorizes drugs by the disease state they are used to treat, appears first, followed by the pharmacologic classification, which is based on the drug’s mechanism of action.) Therapeutic class: antidepressants Pharmacologic class of Fluoxetine: selective serotonin reuptake inhibitors (selective serotonin reuptake inhibitors (SSRIs)… Read More »

Duloxetine 20 mg, 30 mg, 60 mg Capsules

Duloxetine (do-lox-e-teen) [Cymbalta] Duloxetine Classification (The therapeutic classification, which categorizes drugs by the disease state they are used to treat, appears first, followed by the pharmacologic classification, which is based on the drug’s mechanism of action.) Therapeutic class: antidepressants Pharmacologic class of Duloxetine: selective serotonin and norepinephrine reuptake inhibitors — SSNRIs Pregnancy Category (pregnancy categories… Read More »

Drug-centred drug research

The disease-centred model of drug action has restricted our understanding of the effects of drugs used in psychiatry by directing attention to the effects of drugs on a hypothetical disease process and neglecting other areas. For example, although there is ample research about effects of the new generation of antipsychotic drugs on the numerous different… Read More »

CNS Stimulants

Central Nervous System Stimulants Pharmacologic Profile General Use Used in the treatment of narcolepsy and as adjunctive treatment in the management of ADHD. General Action and Information Produce CNS stimulation by increasing levels of neurotransmitters in the CNS. Produce CNS and respiratory stimulation, dilated pupils, increased motor activity and mental alertness, and a diminished sense… Read More »

Antipsychotic Drugs

Pharmacologic Profile General Use Treatment of acute and chronic psychoses, particularly when accompanied by increased psychomotor activity. Use of clozapine is limited to schizophrenia unresponsive to conventional therapy. Selected agents are also used as antihistamines or antiemetics. Chlorpromazine is also used in the treatment of intractable hiccups. General Action and Information Blockdopamine receptors in the… Read More »