Tag Archives: Rizatriptan

Which of the triptans is available in more than one drug delivery formulation?

Which of the triptans listed is available in more than one medication delivery formulation? A. Almotriptan (Axert) B. Rizatriptan (Maxalt) C. Frovatriptan (Frova) D. Naratriptan (Amerge) E. Eletriptan (Relpax) The answer is B. Multiple formulations are currently available for sumatriptan (Imitrex; subcutaneous injection, swallowed tablet, intranasal spray), zolmitriptan (Zomig; swallowed tablet, orally dissolving tablet, intranasal… Read More »

Risk of which is not increased in patients with migraine headaches?

Risk of which of the following is not increased in patients with migraine headaches? A. Arterial dissection B. Subarachnoid hemorrhage (SAH) C. Ischemic stroke D. Myocardial infarct (MI) E. All of the above The answer is B. An association exists between migraine and ischemic cardiovascular and cerebrovascular events, but migraine is not a risk factor… Read More »

Match the triptan with its specific characteristic…

Match the triptan with its specific characteristic. Use each answer only once. A. Sumatriptan (Imitrex) B. Frovatriptan (Frova) C. Naratriptan (Amerge) D. Almotriptan (Axert) E. Rizatriptan (Maxalt) 1. Highest oral bioavailability 2. Lowest oral bioavailability 3. Longest half-life 4. Second longest half-life 5. Shortest time to maximum blood concentration The answer is A 2, B… Read More »

Which triptan is associated with the lowest headache recurrence rate after acute migraine treatment?

Which triptan is associated with the lowest headache recurrence rate after acute migraine treatment? A. Sumatriptan (Imitrex) B. Rizatriptan (Maxalt) C. Frovatriptan (Frova) D. Almotriptan (Axert) E. Naratriptan (Amerge) The answer is C. Frovatriptan (Frova) is a potent 5-HT 1D receptor agonist and has the highest 5-HT1B potency in the triptan class. Frovatriptan has the… Read More »

Headaches and sleep

Which of the following statements best describes headaches and sleep? A. Snoring is correlated with frequent morning headaches. B. The use of continuous positive pressure airway pressure (CPAP) in patients with obstructive sleep apnea (OSA) does not improve frequent morning headaches. C. Gender predilection for OSA mirrors gender predilection for migraine headaches. D. Obstructive sleep… Read More »

Which of the drugs, used to prevent migraine in adults, has been most extensively studied in children and adolescents?

Which of the following medications, used to prevent migraine headaches in adults, has been most extensively studied in children and adolescents? A. Topiramate (Topamax) B. Valproic acid (Depakene) C. Verapamil (Calan) D. Amitriptyline (Elavil) E. Fluoxetine (Prozac) The answer is A. Topiramate (Topamax) has been studied in children with pediatric migraine with or without aura,… Read More »

Which of the short-acting triptans has been shown to prevent menstrual migraine?

Which of the following short-acting triptans has been shown to prevent menstrual migraine in a large, randomized, placebo-controlled trial? A. Zolmitriptan (Zomig) B. Eletriptan (Relpax) C. Sumatriptan (Imitrex) D. Rizatriptan (Maxalt) E. None of the above The answer is A. Currently, no triptan is FDA approved for the short-term, peri-menstrual prevention of menstrual migraine. However,… Read More »

Which of the drug of choice for abortive treatment of a CH?

Which of the following is the drug of choice for abortive treatment of a CH? A. Rectal ergotamine B. Subcutaneous sumatriptan (Imitrex) C. Intranasal zolmitriptan (Zomig) D. Sublingual rizatriptan (Maxalt) E. Oral sumatriptan The answer is B. The pain of a cluster headaches generally lasts 15 to 180 minutes. Because of the CH’s rapid build-up… Read More »

Match the triptan with a description of its delivery systems…

Match the triptan with a description of its delivery systems. Each answer may be used once, multiple times, or not at all. A. Zolmitriptan (Zomig) B. Sumatriptan (Imitrex) C. Rizatriptan (Maxalt) D. Almotriptan (Axert) E. Eletriptan (Relpax) 1. Oral dissolving tablet, swallowed tablet only 2. Swallowed tablet, oral dissolving tablet, intranasal spray 3. Subcutaneous injection,… Read More »

Recommendation for the acute treatment of migraine headaches in children

Which one of the following medications has the highest level of recommendation for the acute treatment of migraine headaches in children? A. Ibuprofen B. Acetaminophen C. Intranasal sumatriptan (Imitrex) D. Subcutaneous sumatriptan E. Oral rizatriptan (Maxalt) The answer is A. Ibuprofen is recommended for the acute treatment of migraine in children. Acetaminophen is probably effective… Read More »