Tag Archives: Scopolamine

Delirium: Etiology

Delirium has a wide variety of etiologies, which may occur alone or in combination (). These include primary cerebral disorders, systemic disturbances that affect cerebral function, drug and toxin exposure (including intoxication and withdrawal), and a range of factors that can contribute to delirium but have an uncertain role as etiological factors by themselves (psychological… Read More »

Beyond Cholinesterase Inhibition

The discovery that the cholinergic system is lost first and to the greatest degree in Alzheimer’s disease unleashed a course of research spanning more than two decades that has resulted in efficacious and targeted therapies for Alzheimer’s disease treatment. The compounds that provided this success were cholinesterase inhibitors but drugs acting upon other transmitter systems… Read More »

Antidementia drugs approved in Germany

In Germany several antidementia drugs have been used for many years, some even for decades. At the end of the 1980s, the Bundesgesundheitsamt and the Bundesinstitut fur Arzneimittel und Medizinprodukte, respectively, introduced a commission to re-evaluate the existing scientific literature about the efficacy of these drugs. Unfortunately, the commission was discharged before its task had… Read More »