Tag Archives: Selective Serotonin Reuptake Inhibitors

Pharmacological Treatment of Dementia

General guidelines for psychotropic medication use in frail elderly patients are applicable. Systematic evidence to support the effectiveness of particular psychotropic drugs in dementia patients is limited. Therefore, choice of drug class may be based on clinical evidence, and choice of agent is often based on the side-effect profile and on the characteristics of a… Read More »

Alzheimer’s Therapy: Antidepressants

Overview. Major depression affects approximately 15% of Alzheimer’s disease patients. By comparison, 5-12% of the general population aged 15 years or older in the major pharmaceutical markets experience at least one episode of major depression per year. Because depression itself may lead to declines in cognition and function, treatment of depression in Alzheimer’s disease patients… Read More »

Bipolar Depression: Antidepressants

Tricyclic Antidepressants Literature is sparse on controlled studies of tricyclic antidepressants for bipolar depression. Tricyclic antidepressants are more effective in the treatment of unipolar depression than in bipolar depression. The risk of switching patients from bipolar depression to mania and of shortening cycle lengths makes tricyclic antidepressants unattractive choices for the treatment of bipolar depression.… Read More »

Social Anxiety Disorder

Epidemiology of Social Anxiety Disorder (SAD) SAD (social anxiety disorder) (social anxiety disorder), also known as social phobia, is characterised by excessive fear of embarrassment or humiliation in social situations, which in turn leads to marked distress or avoidance of these situations and functional impairment as described in DSM-IV-TR. It is a common disorder with… Read More »

Narcolepsy and Other Disorders of Excessive Daytime Sleepiness

Narcolepsy is a prime example of a disorder with dysfunction of a specific sleep state, in this case REM sleep. Isolated fragments of REM sleep intrude into wakefulness, and the result is the characteristic symptoms that invariably cause excessive daytime sleepiness. Narcolepsy in humans was first described in 1880 by the French neurologist Gelineau. Since… Read More »

Treatment of Anxiety in the Medically Ill

Psychotherapy An overemphasis on psychopharmacology in the care of medically ill patients may result in overlooking the value of psychotherapy. The first step in the treatment of anxiety is to spend time listening to and talking with the patient. Just as in psychotherapy with any patient, empathic listening is a powerful tool to relieve distress.… Read More »

BDD and Risperdal

Question. I suffer from body dysmorphic disorder (BDD). I have been taking Paxil for about a year and it has relieved my depression, but not my delusions or referential thinking. The doctor has given me a prescription for Risperdal, which he feels may help me to see things more clearly. I heard it is associated… Read More »

Information about Anxiety Disorders for Patients and Families

Anxiety disorders are a group of disorders that have different causes but share many symptoms. Anxiety disorders are the most common of the psychiatric illnesses. The core symptoms of anxiety disorders are nervousness, worry, and fear. The patient’s symptoms may cause distress and result in some functional impairment. In the spectrum of anxiety disorders, anxieties… Read More »

Information about Alzheimer’s Disease for Patients and Families

Alzheimer’s disease is the most common and well-known form of degenerative dementia. By definition, dementia is a syndrome, a cluster of symptoms, of impaired memory and cognition. Dementia is a cognitive disorder that impairs an individual’s memory and ability for reasoning, awareness, and judgment. Cognitive impairment in Alzheimer’s disease may involve disturbance of language (aphasia),… Read More »

Pharmacologic Treatment in Children and Adolescents for OCD

Clomipramine (Anafranil) Clomipramine (Anafranil), a tricyclic antidepressant (TCA) and potent serotonin re-uptake inhibitor, was used in the first controlled pharmacologic treatment trial in children and adolescents for OCD. Nineteen pediatric patients (mean age, 14.5 ± 2.3 years) were studied in a 12-week double-blind placebo-controlled crossover study (5 weeks of active medication) (). Doses of clomipramine… Read More »