Tag Archives: Thorazine

Pharmacotherapy in the Treatment of People With Schizophrenia

The pharmacological agents most primarily associated with treatment of schizophrenia are grouped in a large and heterogeneous family, the antipsychotics. Recently, this family has been subdivided into the typicals, or neuroleptics, and the atypicals (see Tables Selected Typical Antipsychotic Drugs and Their Characteristics and Atypical Antipsychotics: Relative Potencies and Side Effects). The neuroleptics are so… Read More »

Chronic Illness: Current Therapies

The main goal of bipolar disorder drug treatment is to establish euthymia (stable mood with a persistent sense of well-being) without inducing mania or rapid cycling (i.e., four or more mood episodes in a 12-month period). For this reason, drug treatment usually consists of an agent or, more frequently, combinations of agents that exert both… Read More »

Antipsychotic Drugs Haloperidol Decanoate and Fluphenazine Decanoate

Information About Antipsychotic Drugs Haloperidol Decanoate (Haldol Decanoate) and Fluphenazine Decanoate (Prolixin Decanoate) for Patients and Families Haloperidol decanoate (Haldol Decanoate Injection) and fluphenazine decanoate (Prolixin Decanoate Injection) are long-acting injections of the antipsychotics haloperidol (Haldol) and fluphenazine (Prolixin). In the decanoate formulation, the antipsychotics are suspended in sterile sesame oil to extend the duration… Read More »

Antipsychotic Drug Ziprasidone (Geodon)

Information About Antipsychotic Drug Ziprasidone (Geodon) for Patients and Families Ziprasidone (Geodon) is an antipsychotic drug used in the treatment of psychotic disorders, including schizophrenia, schizoaffective disorder and psychotic depression, and acute mania in bipolar disorder. Ziprasidone is a second-generation antipsychotic, a new class of medicines with actions different from those of the older, first-generation… Read More »

Antipsychotic Drug Quetiapine (Seroquel)

Information About Antipsychotic Drug Quetiapine (Seroquel) for Patients and Families Quetiapine (Seroquel) is an antipsychotic drug used in the treatment of psychotic disorders, including schizophrenia, schizoaffective disorder, psychotic depression, and acute mania in bipolar disorder. Quetiapine is one of the second-generation antipsychotics, a new class of medicines that have actions different from those of older,… Read More »

Antipsychotic Drug Aripiprazole (Abilify)

Information About Antipsychotic Drug Aripiprazole (Abilify) for Patients and Families Aripiprazole (Abilify) is an antipsychotic drug used in the treatment of psychotic disorders, including schizophrenia, schizoaffective disorder, psychotic depression, and acute mania in bipolar disorder. Aripiprazole is a second-generation antipsychotic, a new class of medicines with actions different from those of older, first-generation antipsychotics such… Read More »

Attitudes to the new drugs

In contrast to views about the old drugs, the new generation of drugs introduced into psychiatry from the 1950s onwards were greeted with immense enthusiasm, verging on zeal. One contemporary observer noted disapprovingly that the atmosphere at conferences on the new drugs was akin to religious revivalist meetings. The period is still regarded as one… Read More »

The pharmaceutical industry and the new drugs

The pharmaceutical industry played a significant part in establishing the role of the new psychiatric drugs in the 1950s and 1960s. For doing so it is sometimes credited with helping transform psychiatry into a modern ‘medical specialism’. The large-scale marketing campaigns that helped to establish the use of the early neuroleptic and antidepressant drugs are… Read More »

Drug-centred drug research

The disease-centred model of drug action has restricted our understanding of the effects of drugs used in psychiatry by directing attention to the effects of drugs on a hypothetical disease process and neglecting other areas. For example, although there is ample research about effects of the new generation of antipsychotic drugs on the numerous different… Read More »

Intervention with Families

More than one-third of those who have chronic schizophrenia live with their families, and many others live nearby, so work with families is essential. Families need to be educated about drugs and side effects, how to respond to psychotic behavior, and how to recognize signs of deterioration. They worry about who will take care of… Read More »