Tag Archives: Tranylcypromine

Minor Depression

Etiology and Pathophysiology Minor depression is only a proposed diagnosis in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, and there are no International Classification of Diseases codes to categorize it. The proposed diagnostic category for minor depression in Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition describes a depressive disorder that… Read More »

Specific Migraine-Preventive Agents: Antidepressants

Antidepressants consist of a number of different classes of drugs with different mechanisms of action. Only tricyclic antidepressants (TCAs) have proven efncacy in migraine; we cover the newer components for completeness and reader interest. Mechanism of Action TCAs, selective serotonin-reuptake inhibitors (SSRIs), and serotonin NE-reuptake inhibitors increase synaptic NE or serotonin (5-HT) by inhibiting high-affinity… Read More »

Treatments for Social Phobia

Social phobia was first described as a unique, diagnosable disorder in DSM-III (American Psychiatric Association 1980). From a historical perspective, the disorder has been recognized since the middle of the 19th century, when Casper described erythrophobia (Casper 1902). Marks (1970) separated social phobia from other types of anxiety, including agoraphobia and simple phobia; thus, he… Read More »

Treatment for Anxiety Disorders in the Medically Ill

Treatment of anxiety disorders in the medically ill depends upon the relationship between anxiety symptoms and physical disease. Some patients have persisting symptoms or exacerbations of anxiety disorders that existed before the onset of physical disease. In that case, treatment should be similar to that given to patients without comorbid illness. Other patients, perhaps the… Read More »

Treatment for Social Phobia

Management Effective pharmacological and psychological treatments of social phobia are available. At present, phenelzine is the pharmacological treatment of choice, and cognitive-behavioral group treatment is the psychological treatment of choice for the generalized subtype (). These treatments appear to be about equally effective and, when combined, may work better than either treatment alone. Evidence favoring… Read More »

Pharmacotherapy of Treatment of Depression in Late Life

Antidepressant pharmacotherapy has become the cornerstone of management of depression in late life. Evidence from a number of meta-analyses documents convincingly that antidepressant medications are effective treatments of late-life depression. The newer medications were found to be as effective as tricyclic antidepressants () in these analyses, and generally are associated with fewer discontinuations due to… Read More »

Risk of which is not increased in patients with migraine headaches?

Risk of which of the following is not increased in patients with migraine headaches? A. Arterial dissection B. Subarachnoid hemorrhage (SAH) C. Ischemic stroke D. Myocardial infarct (MI) E. All of the above The answer is B. An association exists between migraine and ischemic cardiovascular and cerebrovascular events, but migraine is not a risk factor… Read More »

Mood disorders: Intervention

As has been indicated, assessment of a primary mood disorder, especially depression, is difficult and involves exploration of many factors, since the mood disorder may be masked by physical problems and other mental disorders. Social workers are trained to look at all of the factors that are impinging on the individual, but they must be… Read More »

Pharmacodynamic Effects of Antidepressants

Antidepressants are not only effective in the treatment of depression but are also used in a variety of other conditions, including panic disorder, obsessive-compulsive disorder, social phobia, anorexia and bulimia nervosa. Since the development of iproniazid in the 1950s, a new antidepressant group has been released almost every decade, with the result that there are… Read More »