Tag Archives: Trihexyphenidyl

Adjunctive Pharmacotherapy and Related Issues

Managing antipsychotic side effects. Antipsychotic drugs produce problematic side effects in many individuals (see Table Side Effects of Typical Antipsychotic Drugs). A major category of side effects results from neurotransmitter dysregulation of the extra-pyramidal motor system. It is thought that these side effects are the result of an imbalance of dopaminergic and acetylcholinergic activity in… Read More »

Common Side Effects: Monitoring and Management Recommendations

Extrapyramidal Side Effects Antipsychotic-induced EPS may occur acutely or after long-term treatment. First-generation antipsychotics, in particular high-potency neuroleptics, are more likely than second-generation antipsychotics to cause EPS when the drugs are used at usual therapeutic doses. However, as can be noted in Table Selected side effects of commonly used antipsychotic medications, considerable variation in the… Read More »

Antipsychotic Drugs Haloperidol Decanoate and Fluphenazine Decanoate

Information About Antipsychotic Drugs Haloperidol Decanoate (Haldol Decanoate) and Fluphenazine Decanoate (Prolixin Decanoate) for Patients and Families Haloperidol decanoate (Haldol Decanoate Injection) and fluphenazine decanoate (Prolixin Decanoate Injection) are long-acting injections of the antipsychotics haloperidol (Haldol) and fluphenazine (Prolixin). In the decanoate formulation, the antipsychotics are suspended in sterile sesame oil to extend the duration… Read More »

Antipsychotic Drug Ziprasidone (Geodon)

Information About Antipsychotic Drug Ziprasidone (Geodon) for Patients and Families Ziprasidone (Geodon) is an antipsychotic drug used in the treatment of psychotic disorders, including schizophrenia, schizoaffective disorder and psychotic depression, and acute mania in bipolar disorder. Ziprasidone is a second-generation antipsychotic, a new class of medicines with actions different from those of the older, first-generation… Read More »

Antipsychotic Drug Risperidone (Risperdal)

Information About Antipsychotic Drug Risperidone (Risperdal and Risperdal Consta) for Patients and Families Risperidone (Risperdal) is an antipsychotic drug used in the treatment of psychotic disorders, including schizophrenia, schizoaffective disorder and psychotic depression, and acute mania in bipolar disorder. Risperidone is a second-generation antipsychotic, a new class of medicines that have actions different from those… Read More »

Antipsychotic Drug Quetiapine (Seroquel)

Information About Antipsychotic Drug Quetiapine (Seroquel) for Patients and Families Quetiapine (Seroquel) is an antipsychotic drug used in the treatment of psychotic disorders, including schizophrenia, schizoaffective disorder, psychotic depression, and acute mania in bipolar disorder. Quetiapine is one of the second-generation antipsychotics, a new class of medicines that have actions different from those of older,… Read More »

Antipsychotic Drug Olanzapine (Zyprexa)

Information About Antipsychotic Drug Olanzapine (Zyprexa) for Patients and Families Olanzapine (Zyprexa) was first marketed in the United States in 1996, primarily for treatment of schizophrenia and schizoaffective disorder. However, olanzapine was also shown to be effective for treating mood disorders, such as bipolar disorder, and received an indication from the U.S. Food and Drug… Read More »

Antipsychotic Drug Aripiprazole (Abilify)

Information About Antipsychotic Drug Aripiprazole (Abilify) for Patients and Families Aripiprazole (Abilify) is an antipsychotic drug used in the treatment of psychotic disorders, including schizophrenia, schizoaffective disorder, psychotic depression, and acute mania in bipolar disorder. Aripiprazole is a second-generation antipsychotic, a new class of medicines with actions different from those of older, first-generation antipsychotics such… Read More »

Delirium: Etiology

Delirium has a wide variety of etiologies, which may occur alone or in combination (). These include primary cerebral disorders, systemic disturbances that affect cerebral function, drug and toxin exposure (including intoxication and withdrawal), and a range of factors that can contribute to delirium but have an uncertain role as etiological factors by themselves (psychological… Read More »

Antipsychotic Drugs

Pharmacologic Profile General Use Treatment of acute and chronic psychoses, particularly when accompanied by increased psychomotor activity. Use of clozapine is limited to schizophrenia unresponsive to conventional therapy. Selected agents are also used as antihistamines or antiemetics. Chlorpromazine is also used in the treatment of intractable hiccups. General Action and Information Blockdopamine receptors in the… Read More »