Tag Archives: Trileptal

Information about Bipolar Disorder for Patients and Families

Bipolar disorder, also called manic-depressive disorder, is a recurrent illness in which the individual’s mood cycles between depression and mania with periods of normality. The illness is a mood disorder. The individual’s moods may swing from manic euphoria, with boundless energy in pursuit of grandiose plans, to depths of depression, with feelings of despair and… Read More »

Chronic Illness: Current Therapies

The main goal of bipolar disorder drug treatment is to establish euthymia (stable mood with a persistent sense of well-being) without inducing mania or rapid cycling (i.e., four or more mood episodes in a 12-month period). For this reason, drug treatment usually consists of an agent or, more frequently, combinations of agents that exert both… Read More »

Treatment Of The Child Or Adolescent With Newly Diagnosed Epilepsy

Paediatric epilepsy is amazingly diverse. In some children, basic diagnosis, seizure classification and treatment are straightforward. Other patients have difficult-to-diagnose seizures, complicated seizure classification and a variable response to treatment. Some seizures are subclinical, others are barely noticeable, and occasionally they are life threatening. Many children with epilepsy have no associated disabilities, but all children… Read More »

Which drugs is most likely to lead to overt hypothyroidism?

Which medication, when given to patients with preexisting treated hypo-thyroidism, is most likely to lead to overt hypothyroidism? A. Lamotrigine (Lamictal) B. Carbamazepine (Tegretol) C. Phenytoin (Dilantin) D. Divalproex sodium (Depakote) E. Gabapentin (Neurontin) The answer is B. Enzyme-inducing antiepilepsy medications, including carbamazepine (Tegretol) and oxcarbazepine (Trileptal), can reduce serum thyroid hormone concentrations through increased… Read More »

Which drug increases the half-life of lamotrigine (Lamictal)?

Which medication increases the half-life of lamotrigine (Lamictal)? A. Topiramate (Topamax) B. Gabapentin (Neurontin) C. Oxcarbazepine (Trileptal) D. Valproic acid (Depakene) or divalproex sodium (Depakote) E. Carbamazepine (Tegretol) The answer is D. Divalproex sodium (Depakote) inhibits the glucuronidation of lamotrigine (Lamictal) and increases its half-life. The dose of lamotrigine needs to be decreased, when combined… Read More »

Which combination of drugs has the greatest risk of serious cutaneous disorders?

Which combination of medications has the greatest risk of serious cutaneous disorders? A. Pregabalin (Lyrica) and valproic acid (Depakene) B. Divalproex sodium (Depakote) and topiramate (Topamax) C. Gabapentin (Neurontin) and lamotrigine (Lamictal) D. Divalproex sodium and lamotrigine (Lamictal) E. Zonisamide (Zonegran) and oxcarbazepine (Trileptal) The answer is D. Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis… Read More »

Which drug can increase the metabolism and decrease the efficacy of oral contraceptives?

Which medication can increase the metabolism and decrease the efficacy of oral contraceptives? A. Tegretol B. Oxcarbazepine (Trileptal) C. Phenytoin (Dilantin) D. Topiramate (Topamax) E. All of the above The answer is E. Medications with predominantly hepatic metabolism may decrease the efficacy of oral contraceptives, especially when higher-thanusual doses of the medications are combined with… Read More »

Which of the drugs is the first choice for a patient with trigeminal neuralgia?

Which of the following medications is the first choice for a patient with trigeminal neuralgia? A. Gabapentin (Neurontin) B. Phenytoin (Dilantin) C. Lioresal D. Lamotrigine (Lamictal) E. Carbamazepine (Tegretol) The answer is E. All of the medications listed are used to prevent the episodic facial pain of trigeminal neuralgia, but carbamazepine (Tegretol), at doses from… Read More »

Which of the medications is approved by the FDA for the treatment of fibromyalgia?

Which of the following medications is approved by the U.S. Food and Drug Administration (FDA) for the treatment of fibromyalgia? A. Gabapentin (Neurontin) B. Pregabalin (Lyrica) C. Intravenous (IV) immunoglobulin D. Oxcarbazepine (Trileptal) E. Nortriptyline (Pamelor) The answer is B. Patients with fibromyalgia, who are generally middle-aged women, complain of diffuse musculoskeletal pain, sleep problems,… Read More »

Antiepileptic Drugs

Antiepileptic drugs are a class of medications developed to treat people with seizures. Tremendous effort and resources have been dedicated to epilepsy research. In the last years new antiepileptic drugs have become available for use. Even more surprisingly, these drugs have been found to improve the lives of people with a variety of medical disorders… Read More »