Tag Archives: Versed

Alzheimer’s Therapy: Gene Therapy

Overview. Gene therapy for Alzheimer’s disease is a long way from being practicable, but some prototypical approaches are being explored. In April 2001, Ceregene, a subsidiary of Cell Genesys, began a Phase I trial for its nerve growth factor (nerve growth factor) gene delivery involving eight patients with early Alzheimer’s disease. Another promising approach pioneered… Read More »

Alzheimer’s Therapy: Beta-Amyloid Immunization

Overview. One of the most exciting prospects in the treatment of Alzheimer’s disease is the development of a therapeutic immunization strategy that could prevent disease progression by clearing amyloid plaques from the brains of Alzheimer’s disease patients. This excitement, however, has been tempered by the discontinuation of the Phase Ha trial of Elan’s vaccine AN-1792… Read More »

Bipolar Depression: Antidepressants

Tricyclic Antidepressants Literature is sparse on controlled studies of tricyclic antidepressants for bipolar depression. Tricyclic antidepressants are more effective in the treatment of unipolar depression than in bipolar depression. The risk of switching patients from bipolar depression to mania and of shortening cycle lengths makes tricyclic antidepressants unattractive choices for the treatment of bipolar depression.… Read More »

Possible Clinical Effects of Neurosteroids

The precise role of neurosteroids in cognition as well as neurological and psychiatric disorders is currently under investigation. Although data from human studies are sparse, results obtained from in vitro and in vivo experiments show promising leads for future clinical applications of neurosteroids. Memory In recent years, memory-enhancing properties have been attributed to pregnenolone and… Read More »

Risperdal for Depression?

Question. My 14-year-old daughter was diagnosed with severe depression. She has been taking 30 mg of Prozac daily for almost a month. Yesterday, she tried to commit suicide by taking 12 diet pills. She has lost 15 pounds. Her psychiatrist has now recommended Risperdal as well. We are worried about the side effects of Risperdal.… Read More »

Schizophrenia: Current Therapies

Etiology and Pathophysiology Schizophrenia has varied and ominous symptoms that generally begin in late adolescence or early adulthood and usually continue throughout life. The diagnostic criteria for schizophrenia have evolved over the past 20 years based on the different iterations of the Diagnostic and Statistical Manual of Mental Disorders and the International Classification of Diseases.… Read More »

Delirium (Acute Confusional State)

Description of Medical Condition Delirium is a neurologic complication of illness and/or medication use that is especially common in older patients. The key diagnostic features are an acute change in mental status that fluctuates, abnormal attention, and either disorganized thinking or altered level of consciousness. Delirium is a medical emergency requiring immediate evaluation in order… Read More »

Psychotic Disorders in Children: Clinical Use of Antipsychotic Medications

Considerations in the Clinical Use of Antipsychotic Medications The following assertions summarize the issues discussed in this post: • Antipsychotic medications are key components in the comprehensive treatment program of severely mood dysregulated children and adolescents with psychotic symptoms, and for children and adolescents with psychotic disorders. • The second generation antipsychotics seem to offer… Read More »

Antipsychotic Drugs Haloperidol Decanoate and Fluphenazine Decanoate

Information About Antipsychotic Drugs Haloperidol Decanoate (Haldol Decanoate) and Fluphenazine Decanoate (Prolixin Decanoate) for Patients and Families Haloperidol decanoate (Haldol Decanoate Injection) and fluphenazine decanoate (Prolixin Decanoate Injection) are long-acting injections of the antipsychotics haloperidol (Haldol) and fluphenazine (Prolixin). In the decanoate formulation, the antipsychotics are suspended in sterile sesame oil to extend the duration… Read More »

Antipsychotic Drug Ziprasidone (Geodon)

Information About Antipsychotic Drug Ziprasidone (Geodon) for Patients and Families Ziprasidone (Geodon) is an antipsychotic drug used in the treatment of psychotic disorders, including schizophrenia, schizoaffective disorder and psychotic depression, and acute mania in bipolar disorder. Ziprasidone is a second-generation antipsychotic, a new class of medicines with actions different from those of the older, first-generation… Read More »